Effects of general and local anesthesia on the pharmacokinetics of cefazolin in patients undergoing orthopedic surgery.

نویسندگان

  • W D Welch
  • J P Jantzen
  • K Johnson
  • R E Bawdon
چکیده

The pharmacokinetics of cefazolin in patients undergoing orthopedic surgery with either general (enflurane) or local (lidocaine or marcaine) anesthesia were studied. No differences in either mean serum levels at 30, 60, or 120 min after the intravenous injection of cefazolin or serum half-lives were seen between the two groups of patients.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 27 5  شماره 

صفحات  -

تاریخ انتشار 1985